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Which of the following is classified as a glucocorticosteroid?

  1. Prednisone

  2. Cortisone

  3. Ibuprofen

  4. Hydrocodone

The correct answer is: Prednisone

Prednisone is classified as a glucocorticosteroid because it is a synthetic form of the naturally occurring hormone cortisol, which is produced in the adrenal glands. Glucocorticosteroids are known for their anti-inflammatory and immunosuppressive properties, making them useful in treating a variety of conditions like allergies, asthma, autoimmune diseases, and more. Prednisone works by decreasing inflammation and modifying the body's immune response. Cortisone is also a glucocorticosteroid, making it another valid choice; however, in this context, the focus is on identifying the specific synthetic steroid primarily used in therapeutic settings for conditions requiring strong anti-inflammatory effects. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID), and hydrocodone is an opioid analgesic, neither of which fall into the category of glucocorticosteroids. Understanding the classification helps in recognizing the specific actions and uses of these medications in clinical practice.